MwPharm++ Release 1.4.0 - Description
contact us

Contact us


Na Viničních horách 1834/24
160 00 Praha 6

Technical support:

Tel: +420 773 760 568

Email: support@mediware.cz

Jiří Douša

Tel: +420 774 435 341

Email: george.dousa@mediware.cz

MwPharm++ Release 1.4.0 - Description

MwPharm++/Edsim++ Release 1.4.0 - Description

  • This release focuses on the implementation of Target Mediated Drug Disposition (TMDD)

  • Added localization into the Czech and Portuguese languages. This version is available in English, Czech, Dutch, German, Korean and Portuguese languages.

  • A dose calculation using a TAbsorption input connected via one or more transit compartments must use diff. equations.

  • Added flow units mL/h and L/min (in addition to L/h and mL/min)

  • Added font size to simulation plot settings (default 10 pts)

  • Added color option to MultiSim plugin

  • Added XCompartment and XPeripheral objects in which the volume of distribution is shared

  • Added two modes to XScaler object: relative (V/Vpop)^expo and absolute (V)^expo

  • Added XScalerExt object for advanced scaling using a variable exponent

  • Moved "Hidden" property to TSymbol class (CR-161) so that it can also be used to show used or hide unused parameters

  • Reintroduced former variable Hidden property as NoPlot property (see CR-161)

  • Added TBinding and TMCompartment objects for modeling target mediated drug disposition

  • Added new driver variable (external) for TOutput and TTransfer objects (Ax refers to A or Atot, Axx always refers to A)

  • Added ForceMolar property to TObject in order allow selection of molar units only. For use in multi-substance objects

  • Added BaseQuantity property to TQuantity in order to identify all quantities that are based on Amount

  • Added MolValue property to TSymbol for retrieving the symbol value in standard molar units

  • Added MolDelta property to TDifVariable for retrieving the variable delta value in standard molar units

  • Added /day units to Flow, Rate, FRate, BRate (new), SRate (new) quantities. Added alternative molar units (mmol/L = mM)

  • Extended batch simulation (CR-138/CR-216). Now a variable dump (*.var) is compared with a reference (*.sim)

  • Clearing a model while a plugin is active may result in a crash (see PR-248).

  • Saving a model while a plugin is active may be missing the latest data if the current plugin.

  • The "No-Interpolation" flag of interpolated variables (TIntVariable) was not persisted.

  • If the first event in a sequence introduces a discontinuity (injection) at a time > 0, a "small step" exception may occur

  • If a quantity contained many units (more than 255 chars) not all would be displayed in the dropdown list

  • The following properties were not preserved with an object type change: obj.Color, obj.Interactant, sym.Unit, var.Color

  • Allometric scaler, covariate, plot variable, event object and profile variable values could not be cleared



MwPharm++ is an efficient TDM software primarily to establish proper dosing regimen based on population PK.

read more


MwPharm Online Calculator is ideal tool for initial dose adjustment based on patient physiology and approate package size selection.

read more

Health insurance

MwPharm Revision System enables better control, more effective treatment and cost savings.

read more

Research & university

Research or teaching on PKPD? Edsim++ is ideal tool for you.

read more
mediware mediware mediware mediware mediware
Try it MWPharm Online