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Jiří Douša

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MwPharm DIS

What is MwPharm/DIS


Download MwPharm DIS here

Is a recombinant software that combines an international Drug Information System (DIS) together with a Therapeutic Drug Monitoring (TDM) solution.

The DIS is provided by Vidal consult and the TDM solution is powered by MWpharm++.



Optimal Pharmacotherapy Scheme


Vidal consult provides information about drugs, interactions between drugs and contraindications of drug usage while MWpharm++ provides first dose adjustment, pharmacogenomics and TDM solution.


MWpharm++ is a software application aimed at clinical pharmacokinetics.

It is used primarily to establish proper dosing regimens using Bayesian estimation based on population pharmacokinetics of the drug and individual patient physiological parameters.


MWpharm++ is a powerful therapeutic drug management tool which is built on Edsim++ platform to enable creation of a user-defined PKPD compartment models and their utilization in MWpharm++ for therapeutic drug management.

Almost 180 drugs are available in the MWpharm++ drug database in October 2014.

For several drugs, modified pharmacokinetic parameters according to genotype/phenotype of the patient are available.

It is possible to add specific pharmacokinetic parameters of the drug for different groups of patients (adults, neonate, patients with specific diagnosis, etc.)

Using the MWpharm++, it is possible to improve the drug prescription quality, adjust drug dose to prevent patient intoxication or underdosage, shift the emphasis in medicine from reaction to prevention and reduce quantity of the plasma drug concentration measurements.

Optimal drug dosing improves quality of life, helps avoid adverse drug reactions and shorten the hospitalization time resulting in the reduction of the overall healthcare costs.


MWpharm++ features

  • Smple installation, user manual and video instructions are available
  • Many graphical users interface
  • Single or server installation
  • Validated against the DOS version of MWpharm, lower computational requirements than MwPharm 4.0
  • Hot keys for quick navigation
  • User accounts
  • Separate patient database for each user or partially/fully shared by users
  • Patient database
  • Patient drug and dosing history
  • Possibility to change drug PK parameters including therapeutic range with no change in the original drug database
  • Possibility to inspect and change the drug model
  • 10 different renal function calculation methods
  • Dose adjustment based on race
  • Regular and Bayesian estimation
  • Exact dosing regimen & 4 practical dosing regimens based on available drug doses and convenient interval times
  • Selected area calculations, e.g. AUC
  • Export to PDF, OpenOffice & MS Office
  • Adaptable output reports
  • Supports parallel calculations processing


VIDAL Consult is the VIDAL decision-support application designed for hospital and private practitioners. It includes complete reference information on drugs available on the market, helps control prescription safety, and allows for management and optimisation of the hospital formulary. VIDAL Consult helps to improve the efficiency of patient management by providing healthcare professionals with access to trusted medical and scientific information on pharmaceutical products.

VIDAL Consult provides rapid access to reference clinical information on drugs, curated by a team of healthcare experts (pharmacists, physicians, pharmacologists) and based on national and international reference sources. With its powerful search engine processing all of these data, VIDAL Consult rapidly identifies specific search terms in 5 categories: Brand name, Active ingredient, Generic, Indication and ATC class.


VIDAL Consult key functionalities

  • Access to reference clinical information on drugs
  • Access to foreign equivalent products (International Brands)
  • Prescription safety checking (based on VIDAL Core’s Decision Support Modules)
  • Hospital formulary management
  • Drug data annotation


(Notice: Text copied form Vidal consult website)



MwPharm++ is an efficient TDM software primarily to establish proper dosing regimen based on population PK.

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MwPharm Online Calculator is ideal tool for initial dose adjustment based on patient physiology and approate package size selection.

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Health insurance

MwPharm Revision System enables better control, more effective treatment and cost savings.

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Research & university

Research or teaching on PKPD? Edsim++ is ideal tool for you.

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